Bilateral symmetrical brain lesions in tricyclic antidepressant overdosage.

نویسنده

  • L M Sabet
چکیده

The cerebral pathology in a case of tricyclic antidepressant overdose by amitriptyline is described. A review of the literature of similar cases is summarized. The relation of the cerebral lesions to the development of a hypertensive episode possibly induced by amitriptyline is discussed.

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Bilateral Symmetrical Brain Lesions in Tricyclic Antidepressant Overdosage

Reprint requests to Dr. L.M. Sabet, Health Sciences Centre, Department of Pathology, London, Canada N6A 5CI. The pathophysiological effects and clinical features of overdosage with tricyclic antidepressants have been described in detail (Moraguerra, 1977; Petit, 1977; Bilgi, 1979). However, published accounts of morphological changes in the brain are scarce and lacking in detail. We are not awa...

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عنوان ژورنال:
  • The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

دوره 7 4  شماره 

صفحات  -

تاریخ انتشار 1980